Serena Williams ambushed by Sofia Kenin at French Open

Serena Williams ambushed by Sofia Kenin at French Open

Her first major tournament back was last year's French Open, where she withdrew before a fourth-round match because of a chest muscle injury.

Illness, but more prominently of late, a knee injury have kept the victor of 23 majors on the sidelines. Siniakova broke Osaka's serve at 4-4 in the first set before the Czech player lost two set points.

Williams, the 10th seed, missed a chance to strike back and was two breaks down when Kenin wrong-footed her with an exceptional forehand into the corner. Then on a second match point, her backhand sailed long.

Naomi Osaka's luck finally ran out at the French Open.

Williams suffered her earliest exit at a Grand Slam tournament since falling in the second round at Roland Garros in 2014.

"We'll see, but I definitely hope so", said the 23-time Grand Slam victor who won seven Wimbledon titles.

And Osaka, so good lately at the biggest moments on her sport's biggest stages, wasn't able to come up with the goods on the hottest day of the tournament so far, with the temperature topping 80 degrees (approaching 30 Celsius).

"I'm definitely feeling short on matches and just getting in the swing of things", she added. Clay is her least effective surface and she has played very little this year, pulling out of her past three tournaments.

But she clearly focused on doing it this year, which she called a mistake. She still won both matches, but Siniakova will present a much stiffer test than Priscilla Hon and Anna Blinkova. I don't want to say I was depressed - that's too strong a statement.

"I just have to keep training hard and put myself in a position again to do it hopefully".

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Another teen is on her way to the French Open 4 round - American Amanda Anisimova.

Siniakova, on the other hand, reached last 16 in a Grand Slam for the first time in career.

It felt like her victory over Azarenka could spark a glittering run but it wasn't to be.

Zverev faces Monte Carlo Masters victor Fabio Fognini, the ninth seed; Thiem's next opponent is French 14 seed and ex-semifinalist Gael Monfils, and eighth-seeded former U.S. Open champion Juan Martin del Potro also made the last 16; just as women's eighth seed Ash Barty and No. 14 Madison Keys. After being taken to three sets in the first two rounds, she dismantled Lesia Tsurenko 6-2, 6-1 to continue the defence of her crown.

Naomi Osaka, however, had an erroneous day at work, hitting 38 unforced errors to surrender the match in one hour and 17 minutes.

Defending champion Simona Halep is the highest seed remaining in the women's draw.

In's men's play, No. 1 Novak Djokovic's streak at majors is now up to 24 matches as he defeated qualifier Salvatore Caruso of Italy 6-3, 6-3, 6-2.

His conqueror in the 2015 final, Wawrinka, collected his 500th career victory by completing a win over Grigor Dimitrov 7-6 (5), 7-6 (4) and 7-6 (8).

Despite being the top seed, Osaka flattered to deceive in Paris.

Osaka has never gone beyond the third round in four appearances at Roland Garros. The Polish teen who just turned 18 Friday, came from a set down to deny gold medalist Monica Puig 0-6, 6-3, 6-3.

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